By Davidta Brown, Senior Staff Editor – The pain, nausea, and light or sound sensitivity that comprise a migraine attack afflict more than 10% of individuals around the world, easily making migraines one of the most globally debilitating diseases of the present day.1 According to the International Headache Society (IHS), migraines are defined by both…

By: Anthony Botte and Tyler Valente, PharmD Candidates c/o 2016 – Diseases which are prevalent within the pediatric population require distinct protocols for treatment accompanied by the utmost care and precision. Pediatric hypertension (HTN) is one disease state in particular that has come to the forefront of medical practice in the United States over the…

By: Erica Dimitropoulos Co-Copy Editor [Content- Focused]  – On February 14, 2014, elosulfase alfa (Vimizim™) became an FDA-approved enzyme replacement therapy for Morquio A Syndrome, a type of mucopolysaccharidosis (MPS IVA).1 Elosulfase alfa was granted priority review and was also the first drug to receive the Rare Pediatric Disease Priority Review Voucher that motivates the development…

By: Fawad Piracha, PharmD Candidate c/o 2016 – Rho Chi Society held its 90th annual meeting on Sunday, March 30, 2014 at the Hyatt Regency Orlando, paralleling the American Pharmacists Association (APhA) 2014 Annual Meeting and Exposition that took place the same weekend. In attendance were delegates and advisors of Rho Chi chapters from pharmacy…

By: Tasnima Nabi, Co-Copy Editor [Content-focused] – On January 23rd, St. John’s University College of Pharmacy and Health Sciences inducted the 2014 Beta Delta Chapter members of Rho Chi Society. The annual induction ceremony took place at the Hillcrest Jewish Center. The inductees include 4th year Pharm.D. students in the top 20% of their class…

By: Davidta Brown, Senior Staff Editor – As the world of healthcare and its provision evolves, laws which organize and oversee the ways that patients receive health services must develop at the same pace. Last November, a new bill establishing clearer protocol for the compounding and tracking of medications became national law. The Drug Quality…

Phi Delta Chi (PDC) is a national professional Pharmacy fraternity, which has been on the St. John’s University campus since 1958. Phi Delta Chi works with many other organizations to advance the science of pharmacy and allied interests both on and off campus. The brothers of Phi Delta Chi have hosted and attended many events,…

The Rho Chi Society is an Academic Honor Society in Pharmacy. Pharmacy students in their professional years of study are invited to join based on academic standing. The Mission of the Society is to encourage and recognize excellence in intellectual achievement and foster fellowship amongst its members. Our Beta Delta Chapter at St. John’s University…

By: Nathan Trustman, PharmD Candidate c/o 2014, AMSCOP at LIU – The antibiotic class known as the fluoroquinolones is widely used in both outpatient and inpatient settings. They provide bactericidal effects by inhibiting DNA gyrase and topoisomerase IV enzymes in bacteria. The systemic agents that are most commonly used in clinical practice include ciprofloxacin, levofloxacin,…

By: Sang Hyo Kim, Staff Editor – On March 29th 2013, the U.S Food and Drug Administration approved canagliflozin (Invokana®), a new form of a diabetic drug for patients with type 2 diabetes mellitus.1 Canagliflozin is in a new class of medications called sodium glucose co-transporter 2 (SGLT2) inhibitors and is the only oral, once-daily…

By: Andy Zhang, PharmD Candidate c/o 2015 – On March 28, 2013, the U.S. Food and Drug Administration announced the approval of Tecfidera™ (dimethyl fumarate) for the treatment of relapsing forms of multiple sclerosis (MS) in adults.1 Tecfidera™ (dimethyl fumarate) will be the third oral drug used for the treatment of MS. The manufacturer Biogen…

By:  Miriam Maltz, PharmD Candidate c/o 2013, AMSCOP, Long Island University – Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by hyperglycemia that is pursuant to insulin resistance, defects in insulin secretion, or both1. Chronic hyperglycemia is associated with detrimental effects on various organ systems that can increase mortality and impact the patient’s…

By:  Bethsy Jacob, PharmD Candidate c/o 2013 – On January 24, 2013, Rho Chi Beta Delta Chapter successfully conducted its annual induction ceremony, welcoming forty-four new members into the chapter.  Membership was granted to students who ranked in the top 20% of their class. This year’s inductees included 4th and 5th year PharmD students as…

By: Mahdieh Danesh Yazdi – The views expressed in this article are solely those of the author and do not reflect the views of the Rho Chi Post, Rho Chi Beta Delta Chapter, or St. John’s University College of Pharmacy and Health Sciences.   For the past few months, I have been on rotation at…

By: Addolorata Ciccone, Co-Copy Editor – Acute Coronary Syndromes Acute coronary syndrome (ACS) is a myocardial ischemia caused by obstruction of coronary arteries.  ACS is stratified into three types, based on electrocardiogram (EKG) changes and the presence of cardiac biomarkers (e.g. troponin, creatinine phosphokinase, and myoglobin).  To guide treatment plans, it is important to identify…

By: Steve P. Soman – Mirabegron (Mybetriq®), known also by the brand name Betanis®in Japan, is a new once daily oral drug.   First in its class, it is a selective β(3)-adrenoceptor agonist that improves symptoms associated with over active bladder (OAB) such as urinary incontinence, urgency, and urinary frequency by enhancing storage function and relaxing…

By: Mohammad A. Rattu, Pharm.D.  [PGY-1 Resident at VA NYHHS] – We sometimes need to step back and look at our foundations for success.  Clearly, without the support of past and present Rho Chi executive boards, there would be no Rho Chi Post newsletter.  From our May to September issues, we will learn about each…

Dear Readers, The Rho Chi Post Editorial Board wishes Dr. Robert A. Mangione and Dr. S. William Zito our warmest congratulations on their recent appointments as Interim Provost and Interim Dean of St. John’s University’s College of Pharmacy and Health Sciences, respectively. Dr. Mangione, affectionately known as Dean Mangione by students, is a well-respected and…

By: Mohamed Dungersi, Associate Student Editor –  What is diabetic ketoacidosis (DKA)? Diabetic ketoacidosis (DKA) is an acute complication of uncontrolled diabetes or hyperglycemia. It is usually observed in cases of extreme hyperglycemia (usually in excess of 500 mg/dl, though it can occur over 250 mg/dl).1,2  It is usually characterized by the presence of hyperglycemia,…

By: Neal Shah, Co Editor-In-Chief – Dyskinesias are abnormal, involuntary movement disorders.  Subsets of dyskinesias include choreas and atheosis.  Chorea is irregular and sporadic contraction of muscles whereas athetosis involves a twisting and writhing of muscles.  These two dyskinesias often occur together and are thus termed choreathetosis.1  Common conditions which feature choreatheosis are Huntington’s, and…

By: Lunbao (Jerry) Huang, Pharm.D.  Candidate c/o 2013 – Pain is a very difficult condition to manage, as clinicians have only subjective findings to work with.  Opioid medications are currently the cornerstones for the management of moderate to severe pain; however, it is often problematic to determine a patient’s real ‘need’ for opioids.  Physicians’ clinical…

By: Michael Maddalena, Pharm.D. Candidate c/o 2016 –       Michael is the upcoming president of the Phi Delta Chi Professional Pharmaceutical Fraternity Beta Alpha Chapter at St.  John’s University College of Pharmacy and Allied Health Professions. The term sophomore comes from a compound of the Greek sophos, meaning “wise”, and moros, meaning “foolish”.  Hence, as…

By: Marie Huang –       Each month, the Rho Chi Post has the wonderful opportunity to sit down with an inspiring leader among the student pharmacists here at St. John’s University College of Pharmacy and Health Sciences – someone who is not afraid to stand apart from the crowd and can be the change he…

By: Lila Ahmed, Pharm.D. Candidate c/o 2013 – Whether you wish to admit it or not, all of us have watched or at least heard of the Dr. Oz Show.  I am sure that many of us encounter patients in the pharmacy who say, “I saw this on Dr. Oz; where could I find it?”…

By: Maria A. Sorbera, Pharm.D. Candidate c/o 2013 –   Maria Sorbera was the 2011-2012 President of the Rho Chi Beta Theta Chapter at the Arnold & Marie Schwartz College of Pharmacy at Long Island University (LIU). She is a strong advocate of networking with fellow pharmacists regardless of their area of expertise, as well…

By: Lauren Kaveski, Pharm.D. Candidate c/o 2013 – We see proton pump inhibitors (PPIs) used in many medication regimens, but it is unknown whether the majority of patients receive these medications for appropriate durations or indications.  For all labeled indications, other than Zollinger-Ellison Syndrome (a rare condition characterized by damaging gastrin hypersecretion and subsequent hydrochloric…

By: Lunbao Huang Pharm D. Candidate c/o 2013 – The seventh report of the Joint National Committee on high blood pressure (JNC-7) states that most classes of antihypertensive drugs such as angiotensin converting enzyme inhibitors (ACEIs), angiotensin-II receptor blockers (ARBs), beta-blockers (BBs), diuretics, and aldosterone-receptor antagonists can be used for hypertensive heart failure patients except…

By: Mahdieh Danesh Yazdi – In previous issues, we discussed prescription drug abuse and several bills currently on the floor of the NYS Legislature, sponsored by Sen. Hannon which addressed the issue. On February 7th, I sat down with Sen. Hannon’s director of communications, Mr. Phil Hecken, and his legislative aide, Mr. Timothy Broschardt to…

By: Nandini Puranprashad, Pharm.D. Candidate c/o 2013 – On January 17, the Rho Chi Beta Delta Chapter at St. John’s University College of Pharmacy and Allied Health Professions held its annual Induction Ceremony at Verdi’s of Whitestone.  Membership is a privilege accorded to the very few who distinguish themselves by their academic and professional achievement.…

By: Neal Shah – There are two major classifications of drug-receptor activity: agonism and antagonism. Agonism occurs when a molecule binds to a receptor, causes an exertion of normal receptor operation, and eventually causes a response. Antagonism of a receptor occurs when a molecule binds to the receptor and does not allow activity to occur.1…

By: Neal Shah – Part I:              Preface. Part II:             Brief review of cardiac electrophysiology. Part III:           Ivabradine as a novel If blocker for the use of stable angina. Part IV:           On the horizon: trimetazidine. – PREFACE When viewed anatomically, the heart may seem like a simple organ.  However, the electrophysiological aspects of the heart are…

By: Maria Sorbera, AMSCOP at LIU, PharmD Candidate c/o 2013 – Maria Sorbera is the President of the Rho Chi Beta Theta Chapter at the Arnold & Marie Schwartz College of Pharmacy at Long Island University (LIU). She is a strong advocate of networking with fellow pharmacists, as well as the need for more unity…

By: Khilna Patel, PharmD Candidate c/o 2012 – Top academic achievement is a plus but is not the only thing to strive for – college is about developing one‘s self as a whole. There are many opportunities to get involved. Don‘t be afraid to try everything that may interest you because it will only bring…

By: Mahdieh Danesh Yazdi – Heart failure is a condition in which the heart cannot pump blood efficiently to adequately perfuse tissues. It is often associated with serious consequences, such as kidney failure, liver dam-age, heart attack, and stroke. Patient care is focused on preventing these complications. Recently, attention has turned to other concerns: studies…

By: Mohamed Dungersi – On behalf of the Rho Chi Honor Society Beta Delta Chapter, it is with immense pleasure that I present to you our monthly newsletter publication, Rho Chi Post. The Rho Chi Honor Society, which is the only national pharmacy honor society of its kind, works to create and recognize lifelong intellectual leaders…