By: Neal Shah, Co-Editor-in-Chief – Duloxetine is a serotonin (5HT) and norepinephrine (NE) reuptake inhibitor (SNRI) introduced to the US market in 2004, indicated for the treatment of diabetic neuropathic pain.1 A chemical figure of duloxetine is shown [in the PDF].2 It was developed in an effort to mimic tricyclic antidepressant mitigation of neuropathic pain…

By: Mahdieh Danesh Yazdi – The views expressed in this article are solely those of the author and do not reflect the views of the Rho Chi Post, Rho Chi Beta Delta Chapter, or St. John’s University College of Pharmacy and Health Sciences.   For the past few months, I have been on rotation at…

By: Neal Shah, Co-Editor-in-Chief – Electroconvulsive therapy (ECT) is a last-line procedure in the treatment of refractory depression, among other neuropsychological disorders.1 By inducing a seizure, neurotransmitters are released and the disease state may feature a modest mitigation in symptoms.1 Seizure medications such as benzodiazepines and barbiturates are prescribed to increase or heighten the seizure…

By: Joo Hee Kwon, Pharm.D. Candidate c/o 2013 – There are 3 antigenic types of influenza: A, B, and C. Influenza C causes mild illness and therefore does not cause epidemics.  In contrast, influenza A and B are capable of causing mild to severe flu and in some cases death.  An epidemic can occur depending…

By: Nandini Puranprashad, Pharm D. Candidate c/o 2013 – I’m sitting in a quaint coffee shop in Cherokee, North Carolina, sipping a dirty chai tea with some of my roommates with 1970s music chiming in the background as I write this article and words cannot describe my experiences at this rotation.  The most surprising aspect…

By: Marina Yermolayeva, PharmD Candidate c/o 2013 – “I’m allergic to the generic; I need the brand name medication,” is a common claim heard by many health care providers.  Managed care organizations get numerous calls from doctors and patients requesting prior authorizations to approve brand name medications whilst there are generic alternatives available on formulary.…

By: James W. Schurr, PharmD Candidate c/o 2014 – Nutrition Support Pharmacy is a specialized practice pertaining to the needs of patients receiving Parenteral (PN) or Enteral Nutrition (EN).  Nutrition Support Pharmacists (NSPs) are integral members of the nutritional support team and bring valuable skills and knowledge to the clinical practice setting.  The Board of…

By: Neal Shah, Co Editor-In-Chief – Pure Red Cell Aplasia (PRCA), also known as erythroblastopenia, is characterized by a suppression of erythrocytes in the bone marrow.  It is a peculiar oddity that the bone marrow’s progenitor cells still differentiate into white blood cells and platelets.1  PRCA has idiopathic, viral, auto-immune, and genetic etiologies.  Diamond-Blackfan syndrome…

By: Mohamed Dungersi & Mahdieh Danesh Yazdi, Associate Student Editors – Each month, the editors at the Rho Chi Post have the opportunity to interview one or more of our faculty members. This month, we had the tremendous opportunity to interview the dean of St. John’s University College of Pharmacy and Allied Health Professions, Dean…

By: Alissa Karr, Purdue University College of Pharmacy Pharm.D. Candidate c/o 2012 –      Alissa Karr is a PharmD Graduate from Purdue University College of Pharmacy, Class of 2012.  She is the current secretary of the American College of Clinical Pharmacy (ACCP) StuNet Advisory Committee.  Her post-graduation plans are to obtain a pharmacy practice…

By: Patrick K. Tabon, Washington State University, PharmD Candidate c/o 2012 – As a graduating student pharmacist I am often asked by others, “What piece of advice do you have for other pharmacy students?” My reply will always be, “Go out there and be involved while you can. Once you find where your passions lie…

By: Mahdieh Danesh Yazdi, with Special Thanks to: Dr. Tomasz Jodlowski – In previous issues, we discussed an upcoming $29.1 billion merger between Express Scripts Inc. and Medco Health Solutions. The merger had been previously delayed by the Federal Trade Commission (FTC). The FTC wanted to verify that this upcoming merger would not violate any antitrust…

By: Shannon Tellier – Medication related problems can be reduced in older adults if the Beers Criteria were utilized by health care professionals. The criteria serves as a guideline to identify potentially inappropriate medications (PIMs) that should be avoided in the elderly population, but it should not replace clinical judgment. This 2012 update includes a…

By: Yufan (Frank) Liu, Pharm.D. Candidate c/o 2013 – Results of numerous epidemiological studies have indicated that having high serum cholesterol can lead to coronary heart disease (CHD). 1 More specifically having high LDL cholesterol puts patients at risk for angina and heart attack.2 To reduce this risk HMG-CoA reductase inhibitors, also known as statins,…

By: Shannon Tellier – Dr. Tran is an assistant clinical professor at St. John’s University College of Pharmacy and Allied Health Professions, and a clinical pharmacy manager in Internal Medicine at NewYork-Presbyterian: Columbia University Medical Center.  She received her BS in Public Health and Doctor of Pharmacy from the University of North Carolina at Chapel…

By: Mahdieh Danesh Yazdi – A few months ago, a new product called AeroShot Pure Energy hit the markets in New York and Massachusetts.  AeroShot is a new inhaler that gives the user bursts of caffeine.  Each inhaler contains an estimated 100mg of caffeine, approximately the same amount as a large cup of coffee.  It…

By: Mahdieh Danesh Yazdi – As previously reported, the recent rise in violence against pharmacies (by people in search of narcotic medications) has riled the New York State legislature into action.  The attorney general has also joined the fray in the fight against prescription drug abuse.  Last June, Attorney General Eric T. Schneiderman, proposed setting…

By: Neal Shah – Osteoporosis is a disease of the bone characterized by decreased bone mineral density (BMD), which reduces the ability of bone to provide adequate structural support.  The main cause of this decreased BMD is inadequate calcium intake or absorption.  The decreased BMD can cause diffuse lesions throughout the skeletal system and can…

By: Aleena Chacko, Long Island University Pharm.D. Candidate c/o 2013 – Established in 1996, Novartis International AG is a multinational pharmaceutical company based in Switzerland.  On January 8, 2012, Novartis issued a recall on some popular over the counter (OTC) medications in the United States (U.S.) over concerns about broken or incorrect tablets ending up…

By: Neal Shah – Anticlotting agents are staples in the prevention and treatment of thrombotic disorders, such as deep vein thrombosis, stroke, pulmonary embolism, myocardial infarction, and atrial fibrillation.1  Intravenous medications, such as unfractionated heparin (UFH), low molecular weight heparin (LMWH), and direct thrombin inhibitors (DTI), are commonly used in, both, inpatient and outpatient settings.…

By: Nataliya Sulyk, PharmD Candidate c/o 2015 – Often waiting until the very last minute to begin studying for finals week, students experience a cycle of stressors. They may be overwhelmed with project deadlines, exhausted from studying for examinations, and/or dependent on caffeine for wakefulness. Fortunately, by developing effective studying habits and strategies, students can…

By: Anon, Pharm.D. Candidate c/o 2012 – This year’s ASHP Midyear Clinical Meeting took place in New Orleans, Louisiana from December 4 – 8, 2011.  It was a keystone moment for many pharmacy students, and especially for those in their final year and in pursuit of a residency, fellowship, or hospital staffing position around the…

By: Neal Shah – There are two major classifications of drug-receptor activity: agonism and antagonism. Agonism occurs when a molecule binds to a receptor, causes an exertion of normal receptor operation, and eventually causes a response. Antagonism of a receptor occurs when a molecule binds to the receptor and does not allow activity to occur.1…

By: Neal Shah – Part I:              Preface. Part II:             Brief review of cardiac electrophysiology. Part III:           Ivabradine as a novel If blocker for the use of stable angina. Part IV:           On the horizon: trimetazidine. – PREFACE When viewed anatomically, the heart may seem like a simple organ.  However, the electrophysiological aspects of the heart are…

By: Jimmy Johnson, PharmD Candidate c/o 2012 – Drug shortages have become more and more of an issue in the health care industry. There are over 200 drugs on the Food and Drug Administration’s (FDA) drug shortage list – a number that has tripled in the last five years.1 The largest impact has been on anesthesia…

By: Mahdieh Danesh Yazdi, with special thanks to Dr. Tomasz Jodlowski – Drug shortages have plagued health care institutions in recent years; they present a serious problem to health care delivery on a national scale. In 2004, there were 58 drug shortages; now, in 2011, this number has increased to 198. Due to limited access…

By: Dr. Bernard Sorofman – Foreword: Dr. Bernard Sorofman is a pharmacy professor and Chair of Pharmacy Practice and Science, as well as the Executive Associate Dean at the College of Pharmacy for the University of Iowa. One of our student editors, Ebey P. Soman, had the privilege to attend and meet Dr. Sorofman at…

By Ebey P. Soman – TNF-alpha inhibitors are drugs used to treat rheumatoid arthritis, Crohn’s disease, and ulcerative colitis, as well as other disease states. These agents suppress the immune system and increase the risk of developing serious infections. Currently, there are five approved drugs in this category: • Adalimumab (Humira®, Abbott) • Certolizumab pegol…