By Nancy Rizkalla, PharmD candidate c/o 2015 –        Percutaneous coronary intervention (PCI) with subsequent stent implantation is a highly effective approach in reducing the risk of death or ischemic complications following a myocardial infarction as well as improving the quality of life in patients with stable angina. PCI is ultimately performed in 60 –…

By: Tamara Yunusova, Staff Editor – On December 3, 2012, the U.S. Second Circuit Court of Appeals became the first court in the nation to authorize off-label drug promotion under the First Amendment.  The heavily-disputed ruling, which is headed for further appeal, will have far-reaching implications for pharmaceutical companies and drug regulation policy. In a…

By: Bhavini Shah, PharmD Candidate c/o 2013  – Fycompa® (perampanel) has received the U.S. Food and Drug Administration (FDA) approval for the adjunctive treatment of partial-onset seizures with or without secondarily generalized seizures in patients with epilepsy aged 12 years and older.1  The drug, manufactured by Eisai Inc., is already approved for use in Iceland,…

By: Bethsy Jacob, PharmD Candidate 2014 – On January 18, 2013, the U.S. Food and Drug Administration (FDA) announced a new approval for Botox, generically known as OnabotulinumtoxinA. Patients diagnosed with urinary incontinence due to an overactive bladder can be prescribed Botox, if they are unable to take or are unresponsive to anticholinergic medications.  This…

By:  Christina Tarantola, PharmD, PGY-1 Resident at Kings Pharmacy – The New York State Department of Health issued a health advisory on November 8, 2012 in response to Hurricane Sandy. The document outlined guidelines on recommended immunizations and disaster relief efforts for volunteers and the general public. Due to an increased risk of exposure to…

By:  Tasnima Nabi, Associate Student Editor – St. John’s University College of Pharmacy and Health Sciences has collaborated with the Union Square Academy of Health Sciences (U. S. A.) to prepare high school students for the pharmacy profession.  This partnership is one of the many projects of the “Urban Pharmaceutical Care, Research and Education Institute,”…

By:  Erica Dimitropoulos, Assistant Student Editor – Although clinical trials can affirm the efficacy and advantages of all marketed medications, it is obvious that patients cannot benefit from a drug that they choose not to take. Therefore, promoting medication adherence is one of the easiest and most affordable ways to improve treatment outcomes. In order…

By:  Lila Ahmed, PharmD Candidate c/o 2013 – In the past, numerous research efforts have attempted to prove the benefits and risks of calcium and multivitamin supplements with little success. Most of the studies performed were inconclusive and did not provide us with significant data; while some studies have found that calcium is beneficial for…

By:  Miriam Maltz, PharmD Candidate c/o 2013, AMSCOP, Long Island University – Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by hyperglycemia that is pursuant to insulin resistance, defects in insulin secretion, or both1. Chronic hyperglycemia is associated with detrimental effects on various organ systems that can increase mortality and impact the patient’s…

By:  Maria Sorbera, PharmD Candidate c/o 2013, AMSCOP, LIU – Hepatitis C is the leading cause of chronic liver disease and cirrhosis, presenting a global health challenge.  Approximately 170 million people worldwide, 3% of the population, are infected with the Hepatitis C Virus (HCV), roughly 3.2 million of whom reside in the United States.  The…

By:  Jena Marion, PharmD Candidate c/o 2013 – It was a few weeks into the spring semester of my freshman year at St. John’s University when I earned my wings.  I was on a plane trip, flying cross-country to San Diego with friends that I had only known for a few months, on my way…

By: Steve Soman, Co-Editor-in-Chief – Varicella Zoster Immune Globulin (Varizig®) was approved by the FDA on December 21st of 2012. The Canadian pharmaceutical company Cangene Corporation, which is owned in-part by Apotex Inc., markets the new product.  The drug was approved by the Food and Drug Administration (FDA) to reduce “the severity of chicken pox…

By: Tamara Yunusova – On Wednesday, July 25th a petition signed by the reform group Physicians for Responsible Opioid Prescribing (PROP) called on the FDA to implement opioid label changes that would restrict Chronic Non-Cancer (CNCP) opioid treatment for patients with severe pain only.  It wasn’t too long before another petition signed by PROP’s adversary,…

By: Katie Cimmino, Pharm D. Candidate c/o 2015 –  With the start of the New Year the French government is enacting a new law concerning contraceptives. Now girls between the ages of 15 to 18 will be able to obtain free birth control.  Not only will they have access to it, but the French government…

By: Alexandra Alleva, PharmD candidate c/o 2013 – As of December 28th, Bristol-Myers Squibb and Pfizer’s brand name oral anticoagulant, Eliquis® (apixaban), attained FDA approval.1  This occurred one month after its approval in  Europe and Canada, following longer than expected waits in the US due to further investigation requests by the FDA.2 The much-anticipated anticoagulant is…

By: Sibyl Cherian, Pharm.D. Candidate c/o 2013 – Last year’s piece on “Carrying the Vincentian Torch” featured the endeavors of the Urban Humanitarian Project (UHP) in order to raise money for their multiple annual charity projects. Since then, the organization has grown and strived to new heights to reach the community around them. 2012 Urban…

By: John S Lim, PharmD Candidate c/o 2013 – America’s focus on healthcare, as well as its position as one of the wealthiest nations of the industrialized world, is incongruous with the consequences of drug shortages suffered by its population. Shortages in pharmaceutical supply compromise quality of life while increasing health care costs. The pharmaceutical…

Dear Readers, Christmas is just a few days away, and an amazing year of great challenges, pleasant surprises, and endeavors is coming to a close.  From working on your Drugs & Diseases courses to simply having the privilege of being part of the profession at the White Coat Ceremony, the students have endured much and…

By: Tamara Yunusova, PharmD Candidate c/o 2017 – Gene therapy? You scoff in disbelief as thoughts of designer babies, liberal eugenics, clones, and ruthless dystopian societies begin to reel in the back of your mind. Perhaps you may even stop to recall a scene or two from Jurassic Park or Star Trek. Undoubtedly, gene therapy…

By Tasnima Nabi, PharmD Candidate c/o 2016 – The FDA has issued warnings on accidental ingestion of over-the-counter eye drops and nasal sprays because they can cause serious harm in children at and under the age of five. Ingestion of as little as 0.6 ml of OTC nasal decongestants and redness-relief eye drops has been…

By: Maria Sorbera, PharmD Candidate c/o 2013 at AMSCOP (LIU) – Author William S. Burroughs states in his novel, “The question is frequently asked: Why does a man become a drug addict?  The answer is that he usually does not intend to become an addict. You don’t wake up one morning and decide to be…

By: Tasnima Nabi, PharmD Candidate c/o 2016 – The most memorable moment of a professional’s career is when he or she is handed a symbol of what represents the culture and esteem of the chosen profession. For pharmacy students embarking upon a very intensive yet rewarding path, a white coat welcomes us into the pharmacy…

By: Mahdieh Danesh Yazdi, Associate Student Editor – For the past few weeks, we have heard about the terrible breakout of fungal meningitis from contaminated methylprednisolone acetate vials manufactured by the New England Compounding Center (NECC).  Approximately 14,000 patients received medication from the contaminated lots.  So far, over 400 cases have been reported and over…

By: Mahdieh Danesh Yazdi, Associate Student Editor – Many of us have prepared for influenza season by receiving the flu vaccine.  (If you have not, please speak to your doctor or pharmacist soon!  Remember: even if you do not need it for your protection, get it for your patients’ well-being).  However, for the youngest members…

By: Elsa Thomas, PharmD Candidate c/o 2013 – Atropine is an anticholinergic used to treat various conditions, such as bradycardia, neuromuscular blockade, mydriasis, nerve agent poisoning, and salivary hypersecretion.1,2  Pharmacologically, it inhibits smooth muscle and glands innervated by postganglionic cholinergic nerves.1,2  It also has functions in the central nervous system (CNS); it could stimulate or…

By: Jessica Lee, PharmD Candidate c/o 2013 – Rheumatoid arthritis (RA) is an autoimmune disease in which the immune system attacks healthy tissue, causing inflammation of the joints and potential harm to other organs.1  It affects 0.5-1% of the adult population and is more prevalent in the seventh decade of life.1  These patients tend to…

By: James W.  Schurr & Stephen Argiro, PharmD Candidates c/o 2014 – Patients frequently utilize non-steroidal anti-inflammatory drugs (NSAIDs) for a wide variety of conditions, including but not limited to arthritis, headaches, and generalized pain.  Despite an excellent safety profile, NSAIDs are associated with certain toxicities, including renal complications (particularly among at risk populations).1  Acute…

By: Shannon Tellier, PharmD Candidate c/o 2013 – Antidepressant discontinuation syndrome has been reported in all categories of antidepressants after an abrupt interruption of therapy.1  Symptoms usually occur within a few days of stopping or reducing the dosage of the antidepressant, and rarely occur with therapy of less than five weeks.1  If left untreated, most…

By: Eugene Kolomiyets, PharmD Candidate c/o 2013, AMSCOP at LIU – Cystic fibrosis (CF) is an autosomal recessive disease caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene located on chromosome 7.1  The disease has been linked to thousands of possible mutations, but only as many as 25-30 are tested for…

By Sunhae Chang, PharmD Candidate c/o 2013 – When patients complain of heartburn, the blame usually shifts to gastroesophageal reflux disease (GERD).  Therefore, patients receive the “standard therapies for GERD”: antacids, histamine-2 receptor antagonists (H2RAs), proton pump inhibitors (PPIs), or prokinetics.1,2  Luckily, most patients respond well to these agents.1,2  Unfortunately, the not-as-lucky ones, despite PPI…

By: Neal Shah, Co-Editor-in-Chief – Duloxetine is a serotonin (5HT) and norepinephrine (NE) reuptake inhibitor (SNRI) introduced to the US market in 2004, indicated for the treatment of diabetic neuropathic pain.1 A chemical figure of duloxetine is shown [in the PDF].2 It was developed in an effort to mimic tricyclic antidepressant mitigation of neuropathic pain…

By: Mahdieh Danesh Yazdi – The views expressed in this article are solely those of the author and do not reflect the views of the Rho Chi Post, Rho Chi Beta Delta Chapter, or St. John’s University College of Pharmacy and Health Sciences.   For the past few months, I have been on rotation at…

By: Neal Shah, Co-Editor-in-Chief – Electroconvulsive therapy (ECT) is a last-line procedure in the treatment of refractory depression, among other neuropsychological disorders.1 By inducing a seizure, neurotransmitters are released and the disease state may feature a modest mitigation in symptoms.1 Seizure medications such as benzodiazepines and barbiturates are prescribed to increase or heighten the seizure…

By: Mahdieh Danesh Yazdi – We live in amazing times. Technology does not progress by steps anymore, it grows by leaps. Health-care has reaped the benefits of these advances just like any other industry. It was not a very long time ago that pharmacists would look up patient records in a book full of names…

By: Elsa Thomas, Pharm.D. c/o 2013 – Human body uses various complex mechanisms to maintain its body temperature within a narrow range despite extreme environmental temperature changes as well as physiological changes. Several factors can affect body temperature such as disease states, growth, exercise, hormonal changes, and medications. Hypothermia can occurs as a result of…

By: Addolorata Ciccone, Student Copy Editor – As a fifth-year pharmacy student researching and ranking advanced pharmacy practice experience (APPE) sites, I felt excited at the prospect of taking the knowledge and skills I obtained in the classroom and applying it to real world patients and scenarios.  My years of work in community pharmacies were…

By: Shannon Tellier – When applying to St. John’s University College of Pharmacy and Health Sciences five years ago, I never would have dreamed that I would have the opportunity to study abroad twice while obtaining my PharmD degree. At the end of my freshmen year, there were rumors about second year pharmacy students having…

By: Mohammad A. Rattu, Pharm.D.  [PGY-1 Resident at VA NYHHS] – We sometimes need to step back and look at our foundations for success.  Without the support of past and present Rho Chi executive boards, there would be no Rho Chi Post newsletter.  From our May to September issues, we will learn about each of…

By: Joo Hee Kwon, Pharm.D. Candidate c/o 2013 – There are 3 antigenic types of influenza: A, B, and C. Influenza C causes mild illness and therefore does not cause epidemics.  In contrast, influenza A and B are capable of causing mild to severe flu and in some cases death.  An epidemic can occur depending…

By: Nandini Puranprashad, Pharm D. Candidate c/o 2013 – I’m sitting in a quaint coffee shop in Cherokee, North Carolina, sipping a dirty chai tea with some of my roommates with 1970s music chiming in the background as I write this article and words cannot describe my experiences at this rotation.  The most surprising aspect…

By: Steve Soman, Pharm.D. Candidate c/o 2013 – Bisphosphonates are proven to enhance bone density and reduce fracture incidence in post-menopausal women but recent data suggests they may have adverse effects with regards to bone quality.  The drugs in this class can be differentiated as non-nitrogen containing (older generation) and nitrogen containing (newer generation) medications.…

By: Addolorata Ciccone, Co-Copy Editor – Acute Coronary Syndromes Acute coronary syndrome (ACS) is a myocardial ischemia caused by obstruction of coronary arteries.  ACS is stratified into three types, based on electrocardiogram (EKG) changes and the presence of cardiac biomarkers (e.g. troponin, creatinine phosphokinase, and myoglobin).  To guide treatment plans, it is important to identify…

By: Mohamed Dungersi, Associate Student Editor – The following address was delivered by one of our student editors on behalf of the students at the College of Pharmacy and Health Sciences as a welcome to St. John’s University to students of the classes of 2016 and 2018. Dean Zito, Administrators, Faculty Members, and students of…

By Nandini Puranprashad, Pharm D. Candidate c/o 2013 – Felipe Camacho is a 6th year student at the University of Florida College of Pharmacy.  He received his Bachelors of Arts in Music Composition from Rollins College, Winter Park, FL.  After graduation, Mr. Camacho plans to pursue a residency at the Veterans Affairs (V.A.), Lee Memorial…

By: Marina Yermolayeva, PharmD Candidate c/o 2013 – “I’m allergic to the generic; I need the brand name medication,” is a common claim heard by many health care providers.  Managed care organizations get numerous calls from doctors and patients requesting prior authorizations to approve brand name medications whilst there are generic alternatives available on formulary.…

By: James W. Schurr, PharmD Candidate c/o 2014 – Nutrition Support Pharmacy is a specialized practice pertaining to the needs of patients receiving Parenteral (PN) or Enteral Nutrition (EN).  Nutrition Support Pharmacists (NSPs) are integral members of the nutritional support team and bring valuable skills and knowledge to the clinical practice setting.  The Board of…

By: Mohammad A. Rattu, Pharm.D.  [PGY-1 Resident at VA NYHHS] – We sometimes need to step back and look at our foundations for success.  Without the support of past and present Rho Chi executive boards, there would be no Rho Chi Post newsletter.  From our May to September issues, we will learn about each of…

By: Neal Shah, Co-Editor-In-Chief – Migraines can be “classic” or “common.”  While all migraines feature unilateral, pulsating headaches, classic migraines feature an “aura” upon onset (whereas common migraines do not).  Pharmacologic treatment of migraines generally includes serotonin agonists (triptans).1 Triptans are selective agonists of the 5-hydroxytryptamine 1B and 1D (5HT1B/1D) subtypes.  By activating these receptors,…

By: Mohamed Dungersi, Associate Student Editor –  Match the following herbal products with their correct description: A. This product has been used to treat liver disease, including hepatitis and cirrhosis.  It has also been used as a protective agent after the liver was exposed to alcohol, acetaminophen, and carbon tetrachloride.B. This product is extracted from…

By: Neal Shah, Co-Editor-in-Chief –  Dialysis is the removal of substances from intravascular circulation by filtration.1  Typically, dialysis is ordered when kidney function declines to 10–15% of normal function.2  The National Kidney Foundation’s Kidney Disease Outcome Quality Initiative (K/DOQI) recommends that planning for dialysis begin when patients reach chronic kidney disease stage 4, which is…