By: Mahdieh Danesh Yazdi – As previously reported, there is currently great concern in the medical community because of the growing number of drug shortages.  Many of these are drugs that are critical to patient care, such as chemotherapy agents and antibiotics.  Last October, President Obama issued an executive order in an attempt to curb…

By: Ebey P. Soman – The FDA recently approved a combination tablet of linagliptin with metformin hydrochloride (Jentadueto®) for the treatment of type 2 diabetes.  Developed by Boehringer Ingelheim and Eli Lilly, the new combination tablet provides a twice-daily treatment option for healthcare providers looking for greater flexibility in treating diabetes. Prescribers may add a…

By: Mohamed Dungersi – On February 28, the U.S. Food and Drug Administration (FDA) approved important safety label changes for the class of cholesterol-lowering drugs known as statins.  Aligned with the FDA’s goal to provide the public with more information for the safe and effective use of statins, the agency made several modifications to the…

By: Mahdieh Danesh Yazdi – A few months ago, a new product called AeroShot Pure Energy hit the markets in New York and Massachusetts.  AeroShot is a new inhaler that gives the user bursts of caffeine.  Each inhaler contains an estimated 100mg of caffeine, approximately the same amount as a large cup of coffee.  It…

By: Mahdieh Danesh Yazdi – As previously reported, the recent rise in violence against pharmacies (by people in search of narcotic medications) has riled the New York State legislature into action.  The attorney general has also joined the fray in the fight against prescription drug abuse.  Last June, Attorney General Eric T. Schneiderman, proposed setting…

By: Mohamed Dungersi – Starting July 1, 2012, Albertans will be able to have their prescriptions renewed at their local pharmacies and pharmacists will receive reimbursements for the service.  Patients will be able to renew medications for blood pressure, birth control, and asthma (particularly, inhalers) without waiting weeks to get into their family doctor’s office.…

By: Mahdieh Danesh Yazdi – Express Scripts Inc., one of the nation’s top pharmacy benefit managers (PBMs), has announced a $29 billion deal to take over one of its top competitors, Medco Health Solutions Inc.  Medco shareholders re-approved the merger on December 21.  For finalization, it needs the approval of Express Scripts’ shareholders and the…

By: Ebey P. Soman – Proton pump inhibitors (PPIs) are medications commonly prescribed to treat heartburn, acid reflux disease, and ulcers.  Almost a vast majority of patients in the United States seem to be taking a PPI, either as a prescription or from over-the-counter (OTC).  Researchers recently discovered associations between the long-term use of PPIs…

By: Ebey P. Soman – New York State’s Elderly Pharmaceutical Insurance Coverage Program (EPIC) is a secondary prescription insurance program for over 280,000 income-eligible seniors aged 65 and older.  The program supplements members’ out-of-pocket Medicare Part D drug plan costs.  To be eligible, the senior must be a state resident with an annual income of…

By: Aleena Chacko, Long Island University Pharm.D. Candidate c/o 2013 – Established in 1996, Novartis International AG is a multinational pharmaceutical company based in Switzerland.  On January 8, 2012, Novartis issued a recall on some popular over the counter (OTC) medications in the United States (U.S.) over concerns about broken or incorrect tablets ending up…

By: Alisha Kumar, PharmD Candidate c/o 2012 – Express Scripts proposed a $29 billion acquisition of Medco Health back in July 2011, and Medco’s shareholders almost unanimously accepted the offer.  According to Medco’s press release, the plan was approved by a margin of 99% to 1%, with approximately 72% of its shareholders voting. The two…

By: Mohamed Dungersi – On January 27, the FDA approved Bydureon® (exenatide extended-release) for use in Type 2 Diabetes Mellitus (T2DM), as an adjunct to diet and exercise.  Bydureon®, a product of Amylin Pharmaceuticals, is a modified formulation of the twice-daily injection, Byetta® (exenatide).  It is the first once-a-week medication for T2DM in the market.…

By: Ebey P. Soman – Since its discovery in Tanganyika (modern day Mozambique and Tanzania in Africa) in 1952, Chikungunya virus outbreaks have been documented in Africa, South Asia, and Southeast Asia.  Due to recent globalization and increased travel, infection has also spread outside of tropical regions and even into western nations (such as the…

By: Neal Shah – Anticlotting agents are staples in the prevention and treatment of thrombotic disorders, such as deep vein thrombosis, stroke, pulmonary embolism, myocardial infarction, and atrial fibrillation.1  Intravenous medications, such as unfractionated heparin (UFH), low molecular weight heparin (LMWH), and direct thrombin inhibitors (DTI), are commonly used in, both, inpatient and outpatient settings.…

By: Ebey P. Soman – With clearly established roles for pharmacists, compounding is recognized and upheld as a core foundation of the pharmacy profession.   It allows pharmacists to provide unique and tailored medication regimens for their patients.  The U.S. Food and Drug Administration (FDA) thought otherwise when the agency sued Franck’s Lab, Inc., a Florida-based…

By: Gokul Kalla, Pharm.D. Candidate c/o 2013 – Hypertension is a chronic disease that affects one out of every three Americans.  Leaving the condition untreated could increase the risk of serious health consequences such as a stroke or a heart attack.  On December 21, the FDA approved Takeda Pharmaceuticals’ Edarbyclor® (azilsartan medoxomil and chlorthalidone) for…

By Jena Marion, Pharm.D. Candidate c/o 2013 – On December 12, 2011, the Administrator of the Drug Enforcement Agency (DEA) ruled to place carisoprodol (Soma®) into Schedule IV of the Controlled Substances Act (CSA).  Carisoprodol has been in use since it was approved for marketing in the U.S. in 1959 with the indication of “relief…

By: Mahdieh Danesh Yazdi – We have all heard the mortifying tales of recent attacks on pharmacies by addicts looking to steal prescription pain-killers. Most notable perhaps, was the case of David Laffers. Mr. Laffers walked into Haven Drugs in Medford, NY and killed the pharmacist, a store clerk, and two customers, who happened to…

By: Mahdieh Danesh Yazdi – In previous issues, we mentioned Bill 5502, which would prohibit insurers from requiring their patients to use mail-order pharmacies.  The legislature modified the bill to mention that the community pharmacies must provide the same price as mail-order pharmacies and not just “comparable,” as was previously written.  The language of the…

By: Bibin Thomas, Long Island University, PharmD Candidate – Earlier in 2011, it was reported that that young and middle-aged HIV positive patients did not need to receive routine Bone Mineral Density (BMD) tests.  BMD helps to identify patients who are at a high risk for bone fractures or weakened bone structures (and eventually need…

By: Khilna Patel, Pharm.D. Candidate c/o 2012 – On October 25 of this year, Eli Lilly and Company announced a worldwide market withdrawal of Xigris (drotrecogin alfa), a drug previously indicated to treat severe sepsis in high-risk patients.  Drotrecogin alfa is a recombinant form of human activated protein C.  The efficacy of drotrecogin alfa was…

By: Jimmy Johnson, PharmD Candidate c/o 2012 – Drug shortages have become more and more of an issue in the health care industry. There are over 200 drugs on the Food and Drug Administration’s (FDA) drug shortage list – a number that has tripled in the last five years.1 The largest impact has been on anesthesia…

By: Mahdieh Danesh Yazdi, with special thanks to Dr. Tomasz Jodlowski – Drug shortages have plagued health care institutions in recent years; they present a serious problem to health care delivery on a national scale. In 2004, there were 58 drug shortages; now, in 2011, this number has increased to 198. Due to limited access…

By: Mahdieh Danesh Yazdi – Douglas v. Independent Living Center of Southern California may not sound like the most interesting case, but its outcome has great impact on the lives of millions of people in California and, indeed, the rest of the country. It is one of only one hundred cases that the Supreme Court…

By Ebey P. Soman – TNF-alpha inhibitors are drugs used to treat rheumatoid arthritis, Crohn’s disease, and ulcerative colitis, as well as other disease states. These agents suppress the immune system and increase the risk of developing serious infections. Currently, there are five approved drugs in this category: • Adalimumab (Humira®, Abbott) • Certolizumab pegol…

By: Mahdieh Danesh Yazdi – Once again, Albany is in the setting of a fierce debate on pharmacy. On June 15th, 2011, the New York State Assembly passed Bill 5502, which would forbid insurance companies from mandating the use of mail-order pharmacies for patients under their medication plan. Bill 5502 specifically mandates that medication plans…