By: Katharine Cimmino, Editor-in-Chief – Attention-deficit/hyperactivity disorder (ADHD) is the most common pediatric psychiatric disorder, and it affects the education, social interactions, and over-all wellbeing of both children and adolescents.1 Symptoms of ADHD can persist into adulthood, and those with this disorder are more likely to suffer from other mental health co-morbidities.2 According to guidelines…

By: Benedette Cuffari, BS Toxicology Candidate c/o 2015 – Hemophilia B is an inherited bleeding disorder that is caused by a substantially reduced or complete lack of blood clotting factor IX. Therefore, people suffering from hemophilia B experience bleeding episodes that cause pain, irreversible joint damage, and life threatening hemorrhages. Approximately 28,000 people are currently…

By: Jacqueline Meaney, PharmD Candidate c/o 2015, University at Buffalo: School of Pharmacy and Pharmaceutical Sciences — Psychotropic medications are typically used in conjunction with cognitive behavioral therapy to treat behavioral problems that affect children with autism spectrum disorder (ASD). Symptoms of ASD typically include a need for routines (change intolerance), difficulty with verbal and…

Submit an article and letter of intent To [email protected] View the application: http://rhochistj.org/RhoChiPost/application/ Below are some FAQ; please email us for any other concerns! Who can join the Rho Chi post? Do I have to be a member of Rho Chi? You do not have to be a member of the Rho Chi Honor Society…

By: Andrew Leong, Staff Writer — This year, the FDA approved three new antibiotics to treat acute bacterial skin and skin structure infections (ABSSSI) caused by Staphylococcus aureus, including MRSA. They are dalbavancin (DalvanceTM), tedizolid phosphate (SivextroTM), and oritavancin (OrbactivTM). Dalbavancin was approved on May 23, 2014 and is administered intravenously in two doses (1000…

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By: Diana Gritsenko, PharmD Candidate 2015 – Multiple complications can arise during pregnancy. While venous thromboembolism (VTE) has a prevalence rate of just 0.06% it is one of the leading causes of maternal mortality. It is recommended that at-risk pregnant women receive anticoagulation therapy for a minimum of 3 months and VTE prophylaxis for the…

By: Elissa Tam, PharmD Candidate c/o 2015 – Patients with Type 1 or Type 2 diabetes who cannot control their glucose levels simply by taking oral medications have to inject insulin daily. They also have to measure their glucose levels by using strips and lancets on a regular basis. For patients, especially elderly ones, the…

By: Melissa Roy Co-Copy Editor [Graphics focused] – Our dedicated preceptor Kimberly Defronzo, RPh, MS, MBA is currently a Consumer Safety Officer at the Food and Drug Administration (FDA). She attended the University of Connecticut School of Pharmacy for her Bachelors of Pharmacy. She then went to St. John’s University College of Pharmacy and Health…

By: Anthony Botte and Tyler Valente, PharmD Candidates c/o 2016 – Diseases which are prevalent within the pediatric population require distinct protocols for treatment accompanied by the utmost care and precision. Pediatric hypertension (HTN) is one disease state in particular that has come to the forefront of medical practice in the United States over the…

By: Valentina DiGangi,PharmD Candidate c/o 2017, Brandon Hu, PharmD Candidate c/o 2018, Sang Hyo Kim, Staff Editor, Samantha Lau, PharmD Candidate c/o 2018, and Seowoo Yoon, PharmD Candidate c/o 2018 – What does a clinician do when there is limited access to a particular drug, such as morphine? Should they treat a patient who is…

By: Sherin Pathickal, PharmD Candidate c/o 2016 – In 2006, the Institute of Medicine reported that over 1.5 million people in the US suffered from a medication error, errors that not only cost the economy billions of dollars, but endangered countless lives.1 Each year, approximately 7,000 deaths occur to due to preventable medication related errors.2…

By Davidta Brown, Senior Staff Editor – The idea of granting pharmacists the right to prescribe, as well as to counsel and dispense, has long been a source of controversy among healthcare professionals. A study out of the University of Alberta in Canada, published online in mid-April, provided some much needed concrete data for an…

By: Ada Seldin, Staff Editor – The overuse of antipsychotics in the nursing home population for off-label indications continues to impact patient safety. In 2005, the FDA issued a black box warning that stated, “The treatment of behavioral disorders in elderly patients with dementia with atypical antipsychotic medications is associated with increased mortality.” The evidence…

By: Diana Gritsenko, PharmD Candidate c/o 2015 – Drug overdose is a serious problem in the United States.  In 2010, drug overdose caused more deaths among adults within the ages of 25 and 64 years than motor vehicle accidents. The Center for Disease Control (CDC), ran an analysis that showed drug overdose death rates have…

By: Erica Dimitropoulos Co-Copy Editor [Content- Focused]  – On February 14, 2014, elosulfase alfa (Vimizim™) became an FDA-approved enzyme replacement therapy for Morquio A Syndrome, a type of mucopolysaccharidosis (MPS IVA).1 Elosulfase alfa was granted priority review and was also the first drug to receive the Rare Pediatric Disease Priority Review Voucher that motivates the development…

By: Katharine Cimmino, Editor-in-Chief – Pressure ulcers can be a painful condition decreasing the quality of life of patients and prolonging hospital stays.1 About 10% of hospital inpatients and 26% of hospice admissions have pressure sores.2 Pressure ulcers are injuries that occur when pressure is applied for prolonged periods of time over bony prominences.1 There…

By: Hayeon Na, Co-Copy Editor (Content Focused) – On February 26th, 2014, pharmacists, clinical faculty, and pharmacy students from St. John’s University College of Pharmacy and Health Sciences gathered at the Freeport Memorial Library for a “Brown Bag,” one of the yearly calendar events at the public library. This event was conducted through the joint…

By: Daniel Mathan, PharmD Candidate c/o 2016, Anita Kachappilly, PharmD Candidate c/o 2016, & Amrita Singh, PharmD Candidate c/o 2015 – Systemic lupus erythematosus (SLE) is a debilitating autoimmune disease that affects multiple organs in the body and can potentially become life threatening.1 The incidence of SLE is about 50 cases for every 100,000 people; it…

By: Ada Seldin, Staff Editor – Since the first release of the Surgeon General’s Report on smoking 50 years ago, it has become clear that smoking results in premature death and a myriad of diseases, affecting almost every organ system. Public health initiatives to increase awareness, prevent initiation, and promote smoking cessation have been marginally…

By: Fatema Elias, Staff Writer – With the New Year and everyone committing to their New Year resolutions, more and more patients are coming into the pharmacy asking for recommendations, particularly for weight loss dietary supplements. I hesitate to recommend an over-the-counter dietary supplement for weight loss. However, we as pharmacists and pharmacy students have…

By: Tamara Yunusova, Senior Staff Editor – Proton Pump Inhibitors (PPIs) are acid-reducing agents that have multiple uses in the treatment and prophylaxis of conditions such as peptic ulcer diseases, H. Pylori infection, Zollinger-Ellison syndrome, GERD, and NSAID gastroduodenal ulcers. Their versatility in treating a wide range of conditions, unparalleled efficacy over their Histamine-2-receptor antagonist…

By: Aleena Cherian, Co-Copy Editor [Graphics-Focused] and Jenny Prakash, PharmD Candidate c/o 2014 – Starting your rotations in 5th year usually brings mixed emotions. On one hand, it’s a relief to finally be finished with labs and D&Ds…imagine, a whole year without any exams! But on the other hand, now you have to test how…

By: Jenny Park, PharmD Candidate c/o 2015 – On July 12, 2013, the FDA approved afatinib (GilotrifTM) as a new first-line treatment for patients with late-stage non-small cell lung cancer (NSCLC), a type of carcinoma where specific types of epidermal growth factor receptor (EGFR) gene mutations are expressed.1 The drug afatinib irreversibly blocks EGFR, also…

By: Ada Seldin, Staff Editor – On November 22, 2013, simeprevir (Olysio®), a new agent to treat chronic hepatitis C, received approval under the FDA’s priority review program. Simeprevir is an NS3/4A protease inhibitor that blocks the replication of the hepatitis C virus. Two other drugs from the same class, boceprevir and telaprevir, which were…

By: Neal Shah, PharmD, MD/PhD Student c/o 2021, West Virginia University School of Medicine – Methadone is a powerful long-acting mu-opioid agonist that has been traditionally used in the management of chronic pain, treatment of pain refractory to certain opioid agents, and maintenance of opioid addiction.1-5 While neuropathic pain is not traditionally linked to mu-opioid…

By: Samantha Schmidt, PharmD Candidate c/o 2014, Palm Beach Atlantic University – The role of pharmacists in healthcare has grown exponentially over the years. Pharmacists now provide advanced patient-centered care services including coordination of medications during transitions of care, comprehensive medication reviews with medication monitoring, chronic disease management, disease education, prevention and wellness services, and…

By: Hayeon Na, Co-Copy Editor and Sang Hyo Kim, Staff Editor – In Volume 1 Issue1 of the Rho Chi Post, we were honored to have an interview with Sandra Leal, PharmD, MPH, FAPhA, CDE, and Director of Clinical Pharmacy at El Rio Health Center in Tucson, Arizona. She had started a petition to support…

By: Joshua Bliss, PharmD Candidate c/o 2016 – Doctor – a word often utilized by both professionals and the general public alike to describe a physician. “Doctor” finds its origins in the Latin word for “teacher.” The word “physician,” however, carries a more complicated origin. It is derived from Latin’s “physicum,” meaning remedy.1 In Luke…

By: Aleena Cherian, Co-Copy Editor, Graphics Focused – Selecting APPE Rotations You’ve made it past the progression interviews at the end of 2nd year, the White Coat Ceremony, and the mind-boggling compounding and kinetics equations. You’re almost done with those labs and late night D&D study sessions. Now, halfway through the first semester of your…

By: Hayeon Na, Co-Copy Editor [Content-Focused] – The Food and Drug Administration (FDA) announced on July 26th that oral dosage forms of ketoconazole (Nizoral®) should no longer be prescribed as first-line therapy for any fungal infections.1 The label and indication for oral ketoconazole were updated, and a new medication guide was added. Other dosage forms…

By: Katharine Cimmino, Editor-in-Chief & Bharat Kirthivasan, Co-Copy Editor – Frank A. Barile Ph.D. is a Professor of Clinical and Applied Toxicology at St. John’s University.  He is also a St. John’s University alumnus, having received a B.S. in Pharmaceutical Science, an M.S. in Toxicology, and a Ph.D. in Pharmacology.  At St. John’s University, Dr.…

By: Davidta Brown, Staff Editor – When the seasons transition from winter into spring every year, healthcare providers brace for a shift into a time of increased sneezes, requests for cough medication, and vaccinations, otherwise known as flu season. The rounds of illness that pass each year are usually more of an annoyance than a…

By Davidta Brown, Staff Editor – For post-operative pain treatment, few drugs are as trustworthy, as tried-and-true, as codeine. Prescriptive confidence in the analgesic has promoted its use in children recovering from uncomplicated surgeries, but the spate of injuries and deaths of young children who had been given codeine after undergoing adenotonsillectomies has provoked a…

By: Beatrisa Popovitz, Staff Editor –  You may have heard the countless horror stories passed on by upperclassman of how D&Ds seep into the crevices of our brains and take over our psyches to inevitably make us breathe, sleep, and speak pharmacy.  Stressing out over exams and investing what may seem like all of your…

By: Tamara Yunusova, Senior Staff Editor – Approximately 3.2 million Americans have chronic hepatitis C infection.1 While acute cases are not common, rates of chronic hepatitis C continue to surge due to the recent discovery of the virus in 1989 and consequently, the establishment of a test screening for HCV antibodies in 1992.1 HCV has…

By: Ada Seldin PharmD Candidate c/o 2015 – On April 16th, 2013, the FDA approved the labeling change for the reformulated OxyContin® (oxycodone hydrochloride controlled-release) tablets, made by Pharma L.P. This change reflects the abuse-deterrent properties of the reformulated OxyContin®, which were not present in the original formulation approved by the FDA in 1995. OxyContin®…

By: Bharat Kirthivasan, Co-Copy Editor [Content-Focused] – Most people would prefer that a research paper be mandated to disclose its source of funds. For example, if a publication effusively supports a certain drug, we want to know if its parent company is footing the bill. Transparency allows research to be viewed in light of its…

By: Rachna Burman & Rodashi Rahman, PharmD Candidate 2016 – Relay for life (Relay) is a volunteer-based fundraiser to support cancer research by the American Cancer Society. Each April, students of St. Johns University participate in this event.  Relay is a poignant event in which students who are either directly or indirectly affected by cancer…

By: Hayeon Na, Co-Copy Editor [Content-Focused] – On March 22, 2013, Public Broadcasting Service (PBS) aired an episode of “Need to Know” on the safety of low to moderate risk medical devices. The episode closely followed the lawsuit of patient Linda Gross who has pelvic organ prolapse and was advised by her doctor to undergo…

By: Helen Dong, PharmD Candidate c/o 2014  – Pharmacy Day, or Legislative Day, is a whole day affair for pharmacy students to meet and speak to members of the federal and state legislature in order to discuss issues that affect pharmacists and to lobby for our profession. This year’s talking points were expanding immunization rights…

By: Mitesh Patel, PharmD Candidate 2014 – $1.2 trillion- This is what the United States spends on healthcare. At 17% of GDP, this sector accounts for more spending in the U.S. than education, defense, welfare, and pension.1 By 2016, our expenditure on healthcare will rise to $1.6 trillion.1 As our health care spending increases, Americans…

By: Bansri Patel – As of May 1st 2013, Plan B®, the brand name emergency contraception pill will now be available to women aged fifteen and older. It will also be sold in the drug store aisles, as opposed to its current location behind the pharmacy counter. When levonorgestrel (Plan B®) first entered the market,…

By: Bharat Kirthivasan – The UK government might soon become the platform for an explosive debate on the utility and ethics of three-person in vitro fertilization (three-person IVF). According to the Human Fertilization & Embryology Authority, there is no evidence to suggest that any form of IVF is unsafe for the mother or the fetus.…

By: James W. Schurr and David Gao, PharmD Candidates 2014 – A recent Op-ed in Newsday by Allen Frances, MD (of Duke University School of Medicine and chairman of the task force that produced the DSM-IV, the current guidelines for psychiatric disease diagnosis) criticizes the American Psychiatric Association for being “extravagantly indifferent to all matters…

By: Bhavini Shah, PharmD Candidate c/o 2013  – Fycompa® (perampanel) has received the U.S. Food and Drug Administration (FDA) approval for the adjunctive treatment of partial-onset seizures with or without secondarily generalized seizures in patients with epilepsy aged 12 years and older.1  The drug, manufactured by Eisai Inc., is already approved for use in Iceland,…

By:  Jena Marion, PharmD Candidate c/o 2013 – It was a few weeks into the spring semester of my freshman year at St. John’s University when I earned my wings.  I was on a plane trip, flying cross-country to San Diego with friends that I had only known for a few months, on my way…

By:  Monica Correia, PharmD Candidate c/o 2013 – This past year of advanced pharmacy rotations, has been a tremendous learning experience for me; I was exposed to the day to day functions and roles of pharmacists in a multitude of environments.  While each experience allowed me to focus on a different aspect of pharmacy, the…

By: Alexandra Alleva, PharmD candidate c/o 2013 – As of December 28th, Bristol-Myers Squibb and Pfizer’s brand name oral anticoagulant, Eliquis® (apixaban), attained FDA approval.1  This occurred one month after its approval in  Europe and Canada, following longer than expected waits in the US due to further investigation requests by the FDA.2 The much-anticipated anticoagulant is…

By: Jessica Lee, PharmD Candidate c/o 2013 – Rheumatoid arthritis (RA) is an autoimmune disease in which the immune system attacks healthy tissue, causing inflammation of the joints and potential harm to other organs.1  It affects 0.5-1% of the adult population and is more prevalent in the seventh decade of life.1  These patients tend to…