By: Katharine Cimmino, Editor-in-Chief – Attention-deficit/hyperactivity disorder (ADHD) is the most common pediatric psychiatric disorder, and it affects the education, social interactions, and over-all wellbeing of both children and adolescents.1 Symptoms of ADHD can persist into adulthood, and those with this disorder are more likely to suffer from other mental health co-morbidities.2 According to guidelines…

By: Elissa Tam, PharmD Candidate c/o 2015 – Patients with Type 1 or Type 2 diabetes who cannot control their glucose levels simply by taking oral medications have to inject insulin daily. They also have to measure their glucose levels by using strips and lancets on a regular basis. For patients, especially elderly ones, the…

By: Elissa Tam PharmD Candidate c/o 2015 – HIV/AIDS continues to be a persistent problem in the United States and in various countries around the world. In 2010 alone, there were around 47,500 new HIV infections in the United States with about 1.1 million Americans living with HIV at the end of 2010.1 When left…

By: Kenny Ng, STJ AMCP Chapter President, PharmD c/o 2017, Kenny Chan, STJ AMCP Chapter President-Elect, PharmD c/o 2017, Davidta Brown, Senior Staff Editor – While those who work tirelessly to combat the spread of Hepatitis B and C never have a day off, there is one day in the year during which special attention…

By: Sherin Pathickal, PharmD Candidate c/o 2016 – In 2006, the Institute of Medicine reported that over 1.5 million people in the US suffered from a medication error, errors that not only cost the economy billions of dollars, but endangered countless lives.1 Each year, approximately 7,000 deaths occur to due to preventable medication related errors.2…

By: Sean Caltabiano PharmD Candidate c/o 2015, Minjoo Park PharmD Candidate c/o 2015, & Elissa Tam PharmD Candidate c/o 2015 With special thanks to Dr. Vibhuti Arya, PharmD, Assistant Clinical Professor, St. John’s University, the Primary Care Information Project, and the New York City Department of Health and Mental Hygiene, Queens, NY. – As part…

By: Sherin Pathickal, PharmD Candidate c/o 2016 – The mandatory receipt of vaccinations as a preventive public health measure has long been a controversial issue in our society.1 Despite the popular use of immunizations, many reservations about vaccine constituents and their safety have prevailed, leading to increasing numbers of unvaccinated people.1 Opponents of vaccinations have…

By: Diana Gritsenko, PharmD Candidate c/o 2015 – Drug overdose is a serious problem in the United States.  In 2010, drug overdose caused more deaths among adults within the ages of 25 and 64 years than motor vehicle accidents. The Center for Disease Control (CDC), ran an analysis that showed drug overdose death rates have…

By: Davidta Brown, Senior Staff Editor – In 21st century medicine, pharmaceuticals have come to include compounds derived through novel and complex methods. Some of the most recent innovations have been in the form of biologics, therapeutic compounds produced through biological processes.1 Biologics are derived from living cell lines which may be bacterial, yeast, animal,…

By: Jenny Park, PharmD Candidate c/o 2015 – Methadone maintenance therapy is prescribed for opioid dependency. Many HIV patients who were former injection drug abusers rely on methadone maintenance. Although there is limited data, research suggests lamivudine, ritonavir, and zidovudine to be the most common concomitant drugs in methadone associated torsades and prolonged QT interval.1…

By: Fatema Elias, Staff Writer – With the New Year and everyone committing to their New Year resolutions, more and more patients are coming into the pharmacy asking for recommendations, particularly for weight loss dietary supplements. I hesitate to recommend an over-the-counter dietary supplement for weight loss. However, we as pharmacists and pharmacy students have…

By: Jenny Park, PharmD Candidate c/o 2015 – On July 12, 2013, the FDA approved afatinib (GilotrifTM) as a new first-line treatment for patients with late-stage non-small cell lung cancer (NSCLC), a type of carcinoma where specific types of epidermal growth factor receptor (EGFR) gene mutations are expressed.1 The drug afatinib irreversibly blocks EGFR, also…

By: Sang Hyo Kim, Staff Editor – Near the end of December, the pharmaceutical company, MannKind Corp, will submit their clinical data to the U.S Food and Drug Administration for the approval of an inhaled dosage form of insulin, Afrezza®.1 Administered with the Dreamboat inhaler, this inhaled dosage form delivers insulin packaged into single dose…

By: Ramya Mathew, PharmD Candidate c/o 2015 – Vertex Pharmaceuticals, an American biotechnology company based in Cambridge, Massachusetts, has been researching a new “nuke” for the treatment of Hepatitis C called VX-135. This nucleotide polymerase inhibitor is currently undergoing clinical trials, but the FDA has put the research on a partial hold due to findings…

By: Samantha Schmidt, PharmD Candidate c/o 2014, Palm Beach Atlantic University – The role of pharmacists in healthcare has grown exponentially over the years. Pharmacists now provide advanced patient-centered care services including coordination of medications during transitions of care, comprehensive medication reviews with medication monitoring, chronic disease management, disease education, prevention and wellness services, and…

By: Arya Mathew, PharmD Candidate c/o 2014 –  About twelve percent of the U.S. population suffers from migraines, affecting adult women three times more than adult men.  Migraines are returning attacks of moderate to severe, throbbing or pulsing pain, usually on one side of the head.  Along with the severe pain, migraine sufferers also experience…

By: Joshua Bliss, PharmD Candidate c/o 2016 – Doctor – a word often utilized by both professionals and the general public alike to describe a physician. “Doctor” finds its origins in the Latin word for “teacher.” The word “physician,” however, carries a more complicated origin. It is derived from Latin’s “physicum,” meaning remedy.1 In Luke…

By: Ansel Oommen, BS Toxicology Candidate c/o 2014 – DNA damage is the driving force behind aging, and, on a more serious note, the development of cancers.1 While the stresses of life can be taxing on cells, the human body possesses a remarkable repair mechanism to remedy them. Researchers from the University of Texas Medical…

By: Davidta Brown, Staff Editor – For the estimated 7.5 million individuals in the United States living with iron deficiency anemia (IDA), there is now a new alternative to iron supplements or time-consuming, repetitive infusions. On July 25, 2013, the FDA approved ferric carboxymaltose injection (Injectafer®) for the treatment of IDA, especially in patients who…

By: Tamara Yunusova, Senior Staff Editor – After a lengthy fifteen-year hiatus in recombinant drug approvals, FDA-approved Recombinant Coagulation Factor IX (Rixubis) has mounted to the forefront of Hemophilia B drug therapy. The recombinant coagulation factor gained orphan drug approval on June 26, 2013 for routine prophylaxis, control of bleeding episodes, and perioperative management in…

By: Hayeon Na, Co-Copy Editor [Content-Focused] – The Food and Drug Administration (FDA) announced on July 26th that oral dosage forms of ketoconazole (Nizoral®) should no longer be prescribed as first-line therapy for any fungal infections.1 The label and indication for oral ketoconazole were updated, and a new medication guide was added. Other dosage forms…

By: David Ong, PharmD Candidate c/o 2014 – Manipulating the renin-angiotensin system is one of the many ways drugs are used to treat hypertension. By blocking key steps in the renin-angiotensin cascade, blood pressure decrease may be achieved. Angiotensin II receptor blockers (ARBs) represent one of the drug classes that utilize the aforementioned mechanism. ARBs…

By: Sang Hyo Kim, Staff Editor – On June 27, 2013, the Centers for Disease Control and Prevention (CDC), AIDS.gov, and other national and local entities organized the 19th annual National HIV Testing Day. On this day, the theme of “Take the Test, Take Control” was employed to spread awareness of testing and prevention methods…

By: Davidta Brown, Staff Editor – When the seasons transition from winter into spring every year, healthcare providers brace for a shift into a time of increased sneezes, requests for cough medication, and vaccinations, otherwise known as flu season. The rounds of illness that pass each year are usually more of an annoyance than a…

By: Sang Hyo Kim, Staff Editor – This year, on July 23rd, FDA advisers voted 7 to 6, with one abstention, in favor of approving the drug certolizumab (Cimzia®) for the indication of axial spondyloarthritis (axSpA). axSpA is a chronic imflammatory condition that includes ankylosing spondylitis (AS) and non-radiographic axial spndyloarthristis (nr-axSpA).1,2 axSpA, AS and…

By: Aleena Cherian, Co-Copy Editor [Graphics-Focused] – Attention deficit/hyperactivity disorder (ADHD) is a chronic neurological behavior characterized by persistent patterns of inattention and/or hyperactive behavior, resulting in a wide range of emotional, functional, and neurocognitive impairments.1,2 First line therapy for ADHD consists of stimulant medications together with non-pharmacologic interventions, and has been shown to improve…

By: Efime Popovitz, BS/MD Candidate, Sophie Davis School of Biomedical Education – When Sarah Murnaghan received the long awaited adult lung after years of battling cystic fibrosis, she not only narrowly escaped her death sentence, but also brought to light a plight that thousands of individuals face each day- a struggle for the opportunity to…

By: Nathan Trustman, PharmD Candidate c/o 2013, AMSCOP at LIU – Obesity is defined as having a body mass index (BMI) of 30 kg/m2 or greater. It is thought to be the result of an imbalance between energy intake and energy expenditure, possibly due to a number of genetic and environmental factors.1 It is estimated…

By Taryn Mondiello, PharmD Candidate c/o 2015 – From June 7th to June 9th, pharmacists from all over New York State gathered at the LaGuardia Marriott in East Elmhurst for the 135th annual PSSNY summer convention. The Pharmacists Society of the State of New York, better known as PSSNY, was founded in 1879 and is…

By: Steve Soman, PharmD – India has become a powerhouse in pharmaceutical manufacturing, often supplying generic alternatives at a fraction of the brand name cost to the developing world. Cheaper alternatives make costly drugs more affordable for poorer nations and NGOs.1 Indian manufacturer Biological E. Limited, a biotech firm based in Hyderabad India, signed a…

By: Hayeon Na, Co-Copy Editor [Content-Focused] – On March 22, 2013, Public Broadcasting Service (PBS) aired an episode of “Need to Know” on the safety of low to moderate risk medical devices. The episode closely followed the lawsuit of patient Linda Gross who has pelvic organ prolapse and was advised by her doctor to undergo…

By: Moisey Rafailov, PharmD Candidate c/o 2015 – It was early in the morning on New York’s Route 684 when a car hit a tractor-trailer and continued driving without regard. Imagine that, when later stopped by a police officer, the driver said that the accident was her pharmacist’s fault. What if I were to tell…

By: Fawad Piracha, Pharm. D Candidate c/o 2016 – The 2012-2013 influenza season has developed into one of the greatest nationwide flu outbreaksof the decade.1 Amid this crisis, many flocked to healthcare providers with flu-like symptoms, while others scoured doctors’ offices, clinics, and pharmacies for the vaccine. With the flu claiming many lives throughout the…

By: Tamara Yunusova, Staff Editor – On December 3, 2012, the U.S. Second Circuit Court of Appeals became the first court in the nation to authorize off-label drug promotion under the First Amendment.  The heavily-disputed ruling, which is headed for further appeal, will have far-reaching implications for pharmaceutical companies and drug regulation policy. In a…

By:  Lila Ahmed, PharmD Candidate c/o 2013 – In the past, numerous research efforts have attempted to prove the benefits and risks of calcium and multivitamin supplements with little success. Most of the studies performed were inconclusive and did not provide us with significant data; while some studies have found that calcium is beneficial for…

By: Tamara Yunusova – On Wednesday, July 25th a petition signed by the reform group Physicians for Responsible Opioid Prescribing (PROP) called on the FDA to implement opioid label changes that would restrict Chronic Non-Cancer (CNCP) opioid treatment for patients with severe pain only.  It wasn’t too long before another petition signed by PROP’s adversary,…

By: Katie Cimmino, Pharm D. Candidate c/o 2015 –  With the start of the New Year the French government is enacting a new law concerning contraceptives. Now girls between the ages of 15 to 18 will be able to obtain free birth control.  Not only will they have access to it, but the French government…

By: Jessica Lee, PharmD Candidate c/o 2013 – Rheumatoid arthritis (RA) is an autoimmune disease in which the immune system attacks healthy tissue, causing inflammation of the joints and potential harm to other organs.1  It affects 0.5-1% of the adult population and is more prevalent in the seventh decade of life.1  These patients tend to…

By: Mahdieh Danesh Yazdi – We live in amazing times. Technology does not progress by steps anymore, it grows by leaps. Health-care has reaped the benefits of these advances just like any other industry. It was not a very long time ago that pharmacists would look up patient records in a book full of names…

By: Joo Hee Kwon, Pharm.D. Candidate c/o 2013 – There are 3 antigenic types of influenza: A, B, and C. Influenza C causes mild illness and therefore does not cause epidemics.  In contrast, influenza A and B are capable of causing mild to severe flu and in some cases death.  An epidemic can occur depending…

By: Steve Soman, Pharm.D. Candidate c/o 2013 – Bisphosphonates are proven to enhance bone density and reduce fracture incidence in post-menopausal women but recent data suggests they may have adverse effects with regards to bone quality.  The drugs in this class can be differentiated as non-nitrogen containing (older generation) and nitrogen containing (newer generation) medications.…

By: Addolorata Ciccone, Co-Copy Editor – Acute Coronary Syndromes Acute coronary syndrome (ACS) is a myocardial ischemia caused by obstruction of coronary arteries.  ACS is stratified into three types, based on electrocardiogram (EKG) changes and the presence of cardiac biomarkers (e.g. troponin, creatinine phosphokinase, and myoglobin).  To guide treatment plans, it is important to identify…

 The College of Pharmacy and Allied Health Professions has officially changed its name to the College of Pharmacy and Health Sciences.  This is the college’s second name change since it was established in 1929. In order to truly encompass the current and future educational goals of the College of Pharmacy and Allied Health Professions, the…

By: Steve P. Soman – Mirabegron (Mybetriq®), known also by the brand name Betanis®in Japan, is a new once daily oral drug.   First in its class, it is a selective β(3)-adrenoceptor agonist that improves symptoms associated with over active bladder (OAB) such as urinary incontinence, urgency, and urinary frequency by enhancing storage function and relaxing…

By: Marie Huang – Each month, the Rho Chi Post has the wonderful opportunity to sit down with an inspiring leader among the student pharmacists here at St. John’s University College of Pharmacy and Allied Health Professions – someone who is not afraid to stand apart from the crowd and can be the change he…

By: Marie Huang – The amphitheater at Nassau University Medical Center fills up slowly as Dr. Alan Jay Cohen, a psychiatrist from Oakland, California, makes his way up to the podium to lead a talk about bipolar disorder, specifically differentiating between its presentations in adults versus in developing children. Among nonprofessionals, bipolar disorder is simply…

By: Mohamed Dungersi – Starting July 1, 2012, Albertans will be able to have their prescriptions renewed at their local pharmacies and pharmacists will receive reimbursements for the service.  Patients will be able to renew medications for blood pressure, birth control, and asthma (particularly, inhalers) without waiting weeks to get into their family doctor’s office.…

By: Ronik Saha, Pharm.D. Candidate c/o 2013 – Clopidogrel (Plavix®) is a thienopyridine antiplatelet agent, which exerts its antiplatelet effects via in vivo conversion to an active thiol metabolite that irreversibly blocks the P2Y-12 component of platelet ADP receptors.  This prevents activation of the GP2B/3A complex, thereby preventing platelet aggregation.  Along with aspirin, clopidogrel reduces…

By: Alisha Kumar, PharmD Candidate c/o 2012 – Express Scripts proposed a $29 billion acquisition of Medco Health back in July 2011, and Medco’s shareholders almost unanimously accepted the offer.  According to Medco’s press release, the plan was approved by a margin of 99% to 1%, with approximately 72% of its shareholders voting. The two…

By: Ebey P. Soman – Since its discovery in Tanganyika (modern day Mozambique and Tanzania in Africa) in 1952, Chikungunya virus outbreaks have been documented in Africa, South Asia, and Southeast Asia.  Due to recent globalization and increased travel, infection has also spread outside of tropical regions and even into western nations (such as the…