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New Hepatitis C Drug Receives FDA Approval...
January 1, 2014 - Clinical , Featured By: Ada Seldin, Staff Editor – On November 22, 2013, simeprevir (Olysio®), a new agent to treat chronic hepatitis C, received approval under the FDA’s priority review program. Simeprevir is an NS3/4A protease inhibitor that blocks the replication of the hepatitis C virus. Two other drugs from the same class, boceprevir and telaprevir, which were… |
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Say Hello to JNC8: New Hypertension Guidelines...
January 1, 2014 - Featured , In the News / Politics By: Frances Trosa PharmD Candidate c/o 2015 – After much anticipation, the report from the Eighth Joint National Committee (JNC 8) has arrived! Panel members appointed to the committee have created evidence – based recommendations to assist physicians in managing hypertensive patients. A major difference between the JNC 7 report and the JNC 8 report… |
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The Blunt Truth...
January 1, 2014 - Featured , In the News / Politics By: Katharine Cimmino, Editor-in-Chief – Marijuana, also known as “grass,” “pot,” “joint,” “weed,” “reefer,” “hashish,” and “Mary Jane,” is a very popular illicit drug.1 According to the National Survey on Drug Use and Health, “In 2012, 5.4 million persons aged 12 or older used marijuana on a daily or almost daily basis in the past 12… |
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Direct Association of HIV and Early Kidney Damage in Wo...
January 1, 2014 - Featured , In the News / Politics By: Elizabeth Kopec, PharmD Candidate c/o 2014, South University School of Pharmacy at Columbia, SC – Human immunodeficiency virus (HIV) is a global pandemic, with approximately 35.3 million people infected in 2012. The United States currently has 1.3 million people living with HIV, with 20,000 deaths occurring every year due to acquired immune deficiency syndrome… |
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Newly Approved: Macitentan (Opsumit®)...
December 1, 2013 - Clinical , Featured By: Rebecca Gilene, PharmD Candidate c/o 2014, St. Louis College of Pharmacy – The FDA approved macitentan (Opsumit®) on October 18, 2013 for the treatment of pulmonary arterial hypertension.1 Pulmonary arterial hypertension, often referred to as PAH, is a disease characterized by high blood pressure in the arteries between the heart and lungs. An increase… |
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Hospital Drug Shortages...
December 1, 2013 - Featured , In the News / Politics By: Hamid Razaki, PharmD – Drug shortages seen across pharmacies in the United States continue to be an issue in patient care. A drug product shortage is defined as a supply issue that affects how the pharmacy prepares or dispenses a drug product, or that influences patient care when prescribers must use an alternative agent.1… |
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Possible Mandatory Lung Cancer Screening...
December 1, 2013 - Featured , In the News / Politics By: Jenny Park, PharmD Candidate c/o 2015 – Lung cancer takes away the lives of about 160,000 individuals annually, which is more than a quarter of all cancer deaths.1 The U.S Preventive Service Task Force is now recommending lung cancer screenings for heavy smokers which could save up to 20,000 lives a year (or about 13%… |
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Provider Status for Pharmacists: Call to Action or Dist...
December 1, 2013 - Featured , In the News / Politics By: Samantha Schmidt, PharmD Candidate c/o 2014, Palm Beach Atlantic University – The role of pharmacists in healthcare has grown exponentially over the years. Pharmacists now provide advanced patient-centered care services including coordination of medications during transitions of care, comprehensive medication reviews with medication monitoring, chronic disease management, disease education, prevention and wellness services, and… |
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Meet the President: An Interview with Father Levesque...
December 1, 2013 - Featured , Professional Advice / Opinions By: Beatrice Popovitz, Staff Editor and Ada Seldin, Staff Editor – In August 2013, St. John’s University welcomed Rev. Joseph L. Levesque, C.M., former president of Niagara University, into the community as interim president. Fr. Levesque has an elaborate background in Vincentian leadership and higher education, having taught in various religious institutions such… |
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“Cowcatcher” Enzyme Catching Medical Attention...
November 1, 2013 - Featured , In the News / Politics By: Ansel Oommen, BS Toxicology Candidate c/o 2014 – DNA damage is the driving force behind aging, and, on a more serious note, the development of cancers.1 While the stresses of life can be taxing on cells, the human body possesses a remarkable repair mechanism to remedy them. Researchers from the University of Texas Medical… |
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Ceftriaxone Induced Hemolytic Anemia...
November 1, 2013 - Clinical , Featured By: Samad Tirmizi, PharmD Candidate c/o 2014 – Hemolytic anemia (HA) is a type of anemia that occurs due to the breakdown of red blood cells. It is classified as intrinsic and extrinsic according to causative factors. Medication induced hemolytic anemia is an example of extrinsic, while genetic predisposition is an intrinsic factor. Drug induced… |
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Does Moxifloxacin Increase the Risk of Dysglycemia?...
November 1, 2013 - Clinical , Featured By: Nathan Trustman, PharmD Candidate c/o 2014, AMSCOP at LIU – The antibiotic class known as the fluoroquinolones is widely used in both outpatient and inpatient settings. They provide bactericidal effects by inhibiting DNA gyrase and topoisomerase IV enzymes in bacteria. The systemic agents that are most commonly used in clinical practice include ciprofloxacin, levofloxacin,… |
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Nature’s Remedy… in a More Palatable Dosage Form...
November 1, 2013 - Featured , In the News / Politics By: Davidta Brown, Staff Editor – Pathogenic bacteria have been enemies to human health for centuries. As recently as last month, the Centers for Disease Control published an 80-page document informing the public about America’s biggest microbial threats. Most of the pathogens on the list exhibit antibacterial resistance. One particular bacterial species, ranked at threat… |
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New Drug to Treat HIV-1 Hits the Market...
October 1, 2013 - Clinical , Featured By: Ada Seldin, Staff Editor – On August 12,2013, a new weapon against HIV-1 infection was added to the existing armada. Dolutegravir, the third integrase strand transfer inhibitor to attain FDA approval, targets a protein essential to HIV replication. HIV-1 is the predominant type of HIV virus, the other being HIV-2, which is endogenous to… |
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Ketoconazole No More...
October 1, 2013 - Featured , In the News / Politics By: Hayeon Na, Co-Copy Editor [Content-Focused] – The Food and Drug Administration (FDA) announced on July 26th that oral dosage forms of ketoconazole (Nizoral®) should no longer be prescribed as first-line therapy for any fungal infections.1 The label and indication for oral ketoconazole were updated, and a new medication guide was added. Other dosage forms… |
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Hope For Children with Acute Lymphoblastic Leukemia...
October 1, 2013 - Featured , In the News / Politics By: Ada Seldin, Staff Editor – Emily Whitehead, a 7-year-old girl who fought off relapsing acute lymphoblastic leukemia (ALL), has captured the hearts and prayers of the masses. Her story is an inspiration to those battling any disease with a poor prognosis and particularly holds promise for the 15% of children with ALL resistant to… |
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Meet the Dean: Interview with Dean DiGate...
October 1, 2013 - Featured , Professional Advice / Opinions By: Katharine Cimmino, Editor-in-Chief and Erica Dimitropoulos, Senior Staff Editor – Just last month, St. John’s University College of Pharmacy and Health Sciences kindly welcomed a new Dean into our family, Dean Russell J. DiGate. Dean DiGate is a highly experienced educator and academic leader. He attended the University of Rochester, where… |
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BRAIN Initiative: Mapping the Human Brain...
October 1, 2013 - Featured , In the News / Politics By Erica Dimitropoulos, Senior Staff Editor – If you were in charge of government spending, how would you allocate our funds? Would you put more money into public schools? Restructure the healthcare system? How about a multi-billion dollar project to remap the brain? A few months ago, President Obama announced his plans to invest in… |
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FDA’s New Warning: Acetaminophen Associated with Seri...
September 1, 2013 - Featured , In the News / Politics By: Andy Zhang, PharmD Candidate c/o 2015 – On August 1st, 2013, the U.S. Food and Drug Administration (FDA) released a new warning of serious acetaminophen associated skin reactions, including Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN) and acute generalized exanthematous pustulosis (AGEP).1 Acetaminophen is one of the most widely used over-the-counter (OTC) medication, and… |
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Novel Virus, Standard Vigilance...
September 1, 2013 - Featured , In the News / Politics By: Davidta Brown, Staff Editor – When the seasons transition from winter into spring every year, healthcare providers brace for a shift into a time of increased sneezes, requests for cough medication, and vaccinations, otherwise known as flu season. The rounds of illness that pass each year are usually more of an annoyance than a… |
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Children, Codeine, and Cytochrome P-450...
September 1, 2013 - Clinical , Featured By Davidta Brown, Staff Editor – For post-operative pain treatment, few drugs are as trustworthy, as tried-and-true, as codeine. Prescriptive confidence in the analgesic has promoted its use in children recovering from uncomplicated surgeries, but the spate of injuries and deaths of young children who had been given codeine after undergoing adenotonsillectomies has provoked a… |
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A Close Concurrence on Certolizumab (Cimzia®)...
September 1, 2013 - Clinical , Featured By: Sang Hyo Kim, Staff Editor – This year, on July 23rd, FDA advisers voted 7 to 6, with one abstention, in favor of approving the drug certolizumab (Cimzia®) for the indication of axial spondyloarthritis (axSpA). axSpA is a chronic imflammatory condition that includes ankylosing spondylitis (AS) and non-radiographic axial spndyloarthristis (nr-axSpA).1,2 axSpA, AS and… |
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iPod, iPad, iPhone… iLimb...
August 1, 2013 - Featured , In the News / Politics By: Sang Hyo Kim, Staff Editor – There is a new invention called “i-limb ultra revolution,” which allows amputees to control their prosthetic hands with an Apple® app called “Bioism.” Designed by Touch Bionics in the United Kingdom, the new prosthetic hand has five individually powered fingers, including a powered rotating thumb and an auto-grasp… |
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New Findings Regarding Cardiovascular Adverse Events wi...
August 1, 2013 - Clinical , Featured By: Aleena Cherian, Co-Copy Editor [Graphics-Focused] – Attention deficit/hyperactivity disorder (ADHD) is a chronic neurological behavior characterized by persistent patterns of inattention and/or hyperactive behavior, resulting in a wide range of emotional, functional, and neurocognitive impairments.1,2 First line therapy for ADHD consists of stimulant medications together with non-pharmacologic interventions, and has been shown to improve… |
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Comparison of the New Oral Antithrombotics and Warfarin...
August 1, 2013 - Clinical , Featured By Omar Khalid Pharm.D. Candidate c/o 2014 – The outpour of a multitude of new oral anticoagulants in recent years has health care professionals questioning whether they should switch the patients over, and what new agents should be used. With the recent addition of dabigatran (Pradaxa®) in October 2010, rivaroxaban (Xarelto®) in November 2011, and… |
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Organ Creation Attempts to Answer Shortage Crisis...
August 1, 2013 - Featured , In the News / Politics By: Efime Popovitz, BS/MD Candidate, Sophie Davis School of Biomedical Education – When Sarah Murnaghan received the long awaited adult lung after years of battling cystic fibrosis, she not only narrowly escaped her death sentence, but also brought to light a plight that thousands of individuals face each day- a struggle for the opportunity to… |
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Two New Agents for the Treatment of Obesity...
August 1, 2013 - Clinical , Featured By: Nathan Trustman, PharmD Candidate c/o 2013, AMSCOP at LIU – Obesity is defined as having a body mass index (BMI) of 30 kg/m2 or greater. It is thought to be the result of an imbalance between energy intake and energy expenditure, possibly due to a number of genetic and environmental factors.1 It is estimated… |
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Understanding Opioid Overdose...
July 1, 2013 - Clinical , Featured By: Aleena Cherian, PharmD Candidate c/o 2014 – Although opioid analgesics are among the most effective drugs to treat pain, they are associated with a growing number of public health issues including addiction and severe, often fatal, overdoses. The recent increase in incidences of opioid overdose is directly correlated to rapidly increasing and widespread use… |
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Solving the HCV Enigma: Current and Future Drug Therapy...
July 1, 2013 - Clinical , Featured By: Tamara Yunusova, Senior Staff Editor – Approximately 3.2 million Americans have chronic hepatitis C infection.1 While acute cases are not common, rates of chronic hepatitis C continue to surge due to the recent discovery of the virus in 1989 and consequently, the establishment of a test screening for HCV antibodies in 1992.1 HCV has… |
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Compounding at a Crossroads: New Boundaries in the Afte...
July 1, 2013 - Featured , In the News / Politics Davidta Brown, PharmD Candidate c/o 2017 – The debate on the nature of compounding practice and the extent to which it ought to be regulated has come to the forefront of public attention. Those who regularly follow American news and politics are familiar with the series of events that have led to the present… |
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Faculty Spotlight: Dr. Heather Mavronicolas Forges the ...
July 1, 2013 - Featured , Professional Advice / Opinions By: Tasnima Nabi, Content-focused Co-Copy Editor – The College of Pharmacy and Health Sciences has officially launched a Master of Public Health (MPH) degree program and accepted applications for Fall 2013. Public Health has become an increasingly important area of study over the years as our country experiences rising numbers of chronic disease, health care… |
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Lower Vaccine Costs for Developing Nations...
July 1, 2013 - Featured , In the News / Politics By: Steve Soman, PharmD – India has become a powerhouse in pharmaceutical manufacturing, often supplying generic alternatives at a fraction of the brand name cost to the developing world. Cheaper alternatives make costly drugs more affordable for poorer nations and NGOs.1 Indian manufacturer Biological E. Limited, a biotech firm based in Hyderabad India, signed a… |
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FDA Takes Major Strides Towards Opioid Abuse Prevention...
June 1, 2013 - Featured , In the News / Politics By: Ada Seldin PharmD Candidate c/o 2015 – On April 16th, 2013, the FDA approved the labeling change for the reformulated OxyContin® (oxycodone hydrochloride controlled-release) tablets, made by Pharma L.P. This change reflects the abuse-deterrent properties of the reformulated OxyContin®, which were not present in the original formulation approved by the FDA in 1995. OxyContin®… |
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Helping Solve the Cruel Mystery...
June 1, 2013 - Featured , In the News / Politics By: Erica Dimitropoulos, Senior Staff Editor – Lupus is highly unpredictable and occurs without warning; there is no known cause and no known cure. It affects over 1.5 million Americans, 90% of whom are women between the ages of 15 – 44.1 No two cases of lupus are alike, making it a very difficult disease… |
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FDA Approves Dimethyl Fumarate for Treatment of Relapsi...
June 1, 2013 - Clinical , Featured By: Andy Zhang, PharmD Candidate c/o 2015 – On March 28, 2013, the U.S. Food and Drug Administration announced the approval of Tecfidera™ (dimethyl fumarate) for the treatment of relapsing forms of multiple sclerosis (MS) in adults.1 Tecfidera™ (dimethyl fumarate) will be the third oral drug used for the treatment of MS. The manufacturer Biogen… |
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Interview with Dr. Omudhome Ogbru, Founder of RxEconsul...
June 1, 2013 - Featured , Professional Advice / Opinions By: Steve Soman, PharmD Candidate c/o 2013 – Q: I see that you got your PharmD at the University of the Pacific. Looking back, what made you choose pharmacy and how has this changed over the years of your practice (if it has)? A: I became a pharmacist because I like to care for others… |
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Noninvasive Cancer Screening—Will We Ever Get It Righ...
June 1, 2013 - Clinical , Featured By: Frances Sousonis, Candidate c/o 2017 – Unfortunately, cancer is a disease about which many are able to share stories. All too often, beloved persons are diagnosed with cancer, or, more regrettably, loses their battle with the beast. Colon cancer is the third most common cancer in the United States and around 150,000 people each… |
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Regulation of Low to Moderate Risk Medical Devices by t...
May 1, 2013 - Featured , Professional Advice / Opinions By: Hayeon Na, Co-Copy Editor [Content-Focused] – On March 22, 2013, Public Broadcasting Service (PBS) aired an episode of “Need to Know” on the safety of low to moderate risk medical devices. The episode closely followed the lawsuit of patient Linda Gross who has pelvic organ prolapse and was advised by her doctor to undergo… |
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Purple Glove Syndrome...
May 1, 2013 - Clinical , Featured By: Sharon Janak, PharmD Candidate c/o 2013 – How can we distinguish between vascular injury and Purple Glove Syndrome (an adverse effect of phenytoin)? What are the warning signs and symptoms? Phenytoin is an anticonvulsant used to treat generalized tonic-clonic and partial seizures. It stabilizes neuronal cell membranes of the motor cortex by facilitating the… |
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Pilltalk: Innovation to Simplify Patient Counseling...
May 1, 2013 - Featured , In the News / Politics By: Mitesh Patel, PharmD Candidate 2014 – $1.2 trillion- This is what the United States spends on healthcare. At 17% of GDP, this sector accounts for more spending in the U.S. than education, defense, welfare, and pension.1 By 2016, our expenditure on healthcare will rise to $1.6 trillion.1 As our health care spending increases, Americans… |
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Alzheimer’s Disease On The Rise...
May 1, 2013 - Clinical , Featured By: Ada Seldin – An impending storm is threatening to stagger the health care system and the nation at large. Alzheimer’s disease, which now affects as many as 5.1 million Americans, is projected to triple its toll by 2050, to 13.8 million Americans.1 These sky-rocketing rates can be attributed to aging of the ‘baby boomers.’2… |
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Plan B® Pill Now Available Without Prescription to Wom...
May 1, 2013 - Featured , In the News / Politics By: Bansri Patel – As of May 1st 2013, Plan B®, the brand name emergency contraception pill will now be available to women aged fifteen and older. It will also be sold in the drug store aisles, as opposed to its current location behind the pharmacy counter. When levonorgestrel (Plan B®) first entered the market,… |
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FDA Approves New Drug ‘Tofacitinib’ for Rheumatoid ...
April 1, 2013 - Clinical , Featured By: Erica Dimitropoulos, Senior Staff Editor – Rheumatoid arthritis is a painful and often debilitating autoimmune disease characterized by symmetric polyarthritis, most commonly of the proximal interphalangeal and metacarpophalangeal joints, elbows, knees, ankles, and spine.1 Its clinical manifestations vary, from a slowly progressing onset of fatigue and musculoskeletal discomfort to a sudden and worsening destruction… |
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Three-Person In Vitro Fertilization: Combating Mitochon...
April 1, 2013 - Featured , In the News / Politics By: Bharat Kirthivasan – The UK government might soon become the platform for an explosive debate on the utility and ethics of three-person in vitro fertilization (three-person IVF). According to the Human Fertilization & Embryology Authority, there is no evidence to suggest that any form of IVF is unsafe for the mother or the fetus.… |
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Say Goodbye to Yearly Flu Shots—The Universal Flu Vac...
April 1, 2013 - Clinical , Featured By: Diana Gritsenko, Pharm D. Candidate c/o 2015 – Every flu season, it is the same story: long lines at doctors’ offices and pharmacy counters as patients scramble to get the year’s vaccine before supplies run out. Year after year, doctors and pharmacists groan while explaining over and over again to patients why they need… |
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Increased Costs of Treatment due to the DSM-V: Implicat...
April 1, 2013 - Featured , In the News / Politics By: James W. Schurr and David Gao, PharmD Candidates 2014 – A recent Op-ed in Newsday by Allen Frances, MD (of Duke University School of Medicine and chairman of the task force that produced the DSM-IV, the current guidelines for psychiatric disease diagnosis) criticizes the American Psychiatric Association for being “extravagantly indifferent to all matters… |
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Documentation of Drug Allergies in Hospitalized Older A...
April 1, 2013 - Clinical , Featured By: Nandini Puranprashad, PharmD Candidate; Sibyl Cherian, PharmD Candidate; Tracey Cannova, PharmD Candidate; and Olga HilasPharmD, MPH, BCPS, CGP – Adverse drug reactions are estimated to occur in 10-20% of hospitalized patients and in 7% of the general population.1 One-third of these reactions are of an allergic or pseudo-allergic nature. The consequences of these hypersensitivity… |
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U.S. v Caronia: Misdemeanor or Constitutional Right?...
March 1, 2013 - Featured , In the News / Politics By: Tamara Yunusova, Staff Editor – On December 3, 2012, the U.S. Second Circuit Court of Appeals became the first court in the nation to authorize off-label drug promotion under the First Amendment. The heavily-disputed ruling, which is headed for further appeal, will have far-reaching implications for pharmaceutical companies and drug regulation policy. In a… |
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New FDA Approval: Fycompa® to Treat Seizures...
March 1, 2013 - Clinical , Featured By: Bhavini Shah, PharmD Candidate c/o 2013 – Fycompa® (perampanel) has received the U.S. Food and Drug Administration (FDA) approval for the adjunctive treatment of partial-onset seizures with or without secondarily generalized seizures in patients with epilepsy aged 12 years and older.1 The drug, manufactured by Eisai Inc., is already approved for use in Iceland,… |
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FDA Approves New Indication for Botox (Onabotulinumtoxi...
March 1, 2013 - Clinical , Featured By: Bethsy Jacob, PharmD Candidate 2014 – On January 18, 2013, the U.S. Food and Drug Administration (FDA) announced a new approval for Botox, generically known as OnabotulinumtoxinA. Patients diagnosed with urinary incontinence due to an overactive bladder can be prescribed Botox, if they are unable to take or are unresponsive to anticholinergic medications. This… |
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